商品编号


IHPAI-P1NBD



品牌


Innovative Research



公司


Innovative Research



公司分类


Proteins



Size

1.0mg

商品信息

Product Description
Human PAI-1 N
BD
labeled at the scissile bond of the reactive loop
P1'-N
BD
PAI-1 was created by mutagenesis of the methionine residue (Met347) at the P1-P1' scissile bond to cysteine. This then provides a free thiol group for N
BD
labeling, a fluorescent probe highly sensitive to changes in solvation and hydrophobic environment. The fluorescence emission of P1'-N
BD
PAI-1 is quenched upon cleavage of the reactive center loop by a target proteinase.
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