商品编号


IRKFAP0318



品牌


Innovative Research



公司


Innovative Research



公司分类


Proteins



Size

5ug

商品信息

Product Description
Recombinant Mouse FGF basic (FGF-2)
In normal tissue, basic fibroblast growth factor is present in basement membranes and in the subendothelial extracellular matrix of blood vessels. It stays membrane-bound as long as there is no signal peptide. It has been hypothesized that, during both wound healing of normal tissues and tumor development, the action of heparan sulfate-degr
ADI
ng enzymes activates bFGF, thus mediating the formation of new blood vessels, a process known as angiogenesis. In addition, it is synthesized and secreted by human
ADI
pocytes and the concentration of bFGF correlates with the BMI in blood samples. In this study, bFGF was also shown to act on preosteoblasts - in the form of an increased proliferationdisambiguation needed - after binding to fibroblast growth factor receptor 1 and activating phosphoinositide 3-kinase.3bFGF has been shown in preliminary animal studies to protect the heart from injury associated with a heart attack, reducing tissue death and promoting improved function after reperfusion.
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