商品编号


IRKFAP0276



品牌


Innovative Research



公司


Innovative Research



公司分类


Proteins



Size

100ug

商品信息

Product Description
Recombinant Mouse IL-1 beta
The IL-1 family of cytokines encompasses eleven proteins that each share a similar -barrel structure and bind to Ig-like receptors. Several of the well characterized members of the IL-1-like cytokines play key roles in the development and regulation of inflammation. IL-1 (IL-1F1), IL-1 (IL-1F2), and IL-18 (IL-1F4) are well-known inflammatory cytokines active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. In contrast, IL-1 receptor antago
NIST
(IL-1ra; IL-1F3) and IL-36 receptor antago
NIST
(IL-36ra; IL-1F5) reduce inflammation by blocking the binding of the ago
NIST
receptor ligands. IL-33 (IL-1F11) is thought to function as an 'alarmin' released following cell necrosis to alerting the immune system to tissue damage or stress. The
BIOLOG
ical properties of IL-37 (IL-1F7) are mainly those of down-regulating inflammation.
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