商品编号


JP10417



品牌


IBL



公司


IBL,inc



公司分类


Antibodies


商品信息

Quantity / Tests
100 ?g
Species / Antigen
Recombinant protein of human angiotensinogen
Host
Mouse
Subclass / Clone
IgG1/104AT 601.2.80
Type
No
Purification
Affinity purified with Protein A
Label
No
Regulatory Status:
For research use only


Details for:


?
Anti-Human Angiotensinogen (104AT 6012.80) Mouse IgG

Angiotensinogen is the precursor of angiotensin and is cleaved into angiotensin I and II in the renin-angiotensin system, and it has long been reported to play an important role in controlling blood pressure. In recent years interest related to the role of the renin-angiotensin system in arterial pressure control and the pathophysiology of hypertension has been shifting to its local role in various tissues. Among the studies urinary excretion of angiotensinogen in a rat model of angiotensin II (AII)-dependent hypertension has been reported to be a
Marker
of the activity of the local intrarenal renin-angiotensin system. Intrarenal AII increases to an extent in AII-dependent hypertension that cannot be explained by the plasma AII equilibration alone, and two mechanisms, an increase in intracellular uptake of AII and an increase in intrarenal expression of angiotensinogen, have been proposed to explain it.

Distributed by
IBL
International

For concrete data please consult the Instruction for Use in the download box on the right side.