商品编号


JP10357



品牌


IBL



公司


IBL,inc



公司分类


Antibodies


商品信息

Quantity / Tests
100 μg
Species / Antigen
Recombinant protein for Human C-ERC/Mesothelin
Host
Mouse
Subclass / Clone
IgG / 22A31
Type
Monoclonal
Purification
Affinity purified with Protein A
Label
No
Regulatory Status:
For research use only


Details for:


?
Anti-Human C-ERC/Mesothelin (22A31) Mouse IgG MoAb

ERC (Expressed in Renal Carcinoma) gene has been shown to be over-expressed in cancer-affected renal cells in Eker rats (a rat model of renal cancer). The human homologue of the protein is encoded by the gene MPF (megakaryocyte potentiating factor) or mesothelin.
It is predominantly present in the mesothelial cells and involved in the development of Mesothelioma. These facts make protein a promising tumor
Marker
.
In addition, it has also been suggested that this protein is associated with the development of pancreatic, ovarian and pulmonary cancers, etc.
The ERC/mesothelin gene (MSLN) encodes a 71-kDa precursor protein, which is cleaved by furin-like protease to yield 31-kDa N-terminal (N-ERC/mesothelin) and 40-kDa C-terminal.
This antibody is specific to C-ERC/Mesothelin (40 kDa fragment).

Distributed by
IBL
International


For concrete data please consult the Instruction for Use in the download box on the right side.