商品编号


AG-40T-0291-C250



品牌


Adipogen



公司


Adipogen



公司分类


Proteins



Size

250 ?g

商品信息


More Information



Product Details



Synonyms

Ubiquitin-like Protein FUBI; 40S Ribosomal Protein S30; Asr1; FAU; Fub1; MNSFβ; RPS30; S30



Product Type

Protein



Properties



Source/Host

E. coli



Sequence

Human MNSF β [FUBI] (Accession Nr. P35544).



Crossreactivity

Human



Formulation

Liquid. In 50mM HEPES pH 8.0, 100mM NaCl, 1mM DTT.



Declaration

Manufactured by Boston Biochem



Shipping and Handling



Shipping

DRY ICE



Short Term Storage

-20°C



Long Term Storage

-80°C



Handling Advice

Aliquot to avoid freeze/thaw cycles.



Use/St
ABI
lity

Stable for at least 1 year after receipt when stored at -80°C.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


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The ubiquitin-like protein MNSFβ (Monoclonal Nonspecific Suppressor Factor β), also called FUBI, is encoded by the FAU gene, and is translated as a pro-form consisting of MNSFβ fused to the ribosomal S30 protein. S30 is cleaved in a post-translational reaction, releasing the mature 74 amino acid MNSFβ protein. MNSFβ has a C-terminal gly-gly motif common to many ubiquitin-like proteins. MNSFβ conjugation to Bcl-G has been shown to regulate the ERK1/2-MAPK cascade in macrophage cell lines, and may be implicated in TLR4-mediated signal transduction. Conjugation to endophilin II regulates dectin-1-mediated phagocytosis and inflammatory responses, and may be implicated in TLR2 signaling pathway.