商品编号


ax4013



品牌


Axolbio



公司


Axolbio



公司分类


Oncology




1 Ea

商品信息
Fulvestrant-Resistant MCF7 Cells (MCF7/182R-6) (1 million cells)
Description:
MCF7/182R-6 is a fulvestrant-resistant MCF7 breast cancer cell line. The parental MCF7/S0.5 line was treated long-term with 100 nM fulvestrant and the surviving clone was expanded as a resistant cell line. To maintain a high level of resistance, the cells are cultured in the presence of 100 nM fulvestrant.

Condition of sale: the end user is not permitted to transfer or re-freeze the cells.
Product Specification:


Donor gender

Female



Donor age at sampling

69 yrs



Genetic modification

None



Size

1 million cells



Growth properties

Adherent



Disease information

Malignant adenocarcinoma derived from pleural?effusion



General notes

Expresses the estrogen receptor (ER); resistant to fulvestrant at 100 nM



Shipping conditions

Dry ice



Storage conditions

Liquid nitrogen



Usage notes

Culture in DMEM/F12 medium (no phenol red) supplemented with 1% fetal bovine serum + 2.5 mM GlutaMAX + 6 ng/mL insulin. Addition of 100 nM fulvestrant is required to maintain a high level of resistance



Condition of sale

The end user is not permitted to transfer or re-freeze the cells