商品编号


K0144-5 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

5 mg

商品信息

Product ID
K0144
Cas No.
97145-43-2
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Kallikrein inhibitor is a serine protease inhibitor that inhibits kallikrein and plasmin. Kallikrein inhibitor may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema. In various cancer cell lines, kallikrein inhibitor alters membrane potential and increases intracellular Ca2+, inhibiting cell proliferation.
Product Info
Cas No.
97145-43-2
Purity
≥95%
Formula
C
35
H
55
N
11
O
9
Formula Wt.
773.9
IUPAC Name
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-acetylpyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]pentanediamide
Synonym
KKI 5
Appearance
White to off white powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
MSD
S
K0144
MSD
S PDF
Info Sheet
K0144 Info Sheet PDF
References
Bilgin M, Burgazli KM, Rafiq A, et al. Effect of bauhinia bauhinioides kallikrein inhibitor on endothelial proliferation and intracellular calcium concentration. Eur Rev Med Pharmacol Sci. 2014 Jan;18(1):46-51. PMID: 24452941.
Nakahata AM, Mayer B, Neth P, et al. Blocking the proliferation of human tumor cell lines by peptidase inhibitors from Bauhinia seeds. Planta Med. 2013 Mar;79(3-4):227-35. PMID: 23345168.
Levy JH, O'Donnell PS. The therapeutic potential of a kallikrein inhibitor for treating hereditary angioedema. Expert Opin Investig Drugs. 2006 Sep;15(9):1077-90. PMID: 16916274.