商品编号


K0276-0.5 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

0.5 mg

商品信息

Product ID
K0276
Cas No.
85916-47-8
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Katacalcin is a polypeptide encoded by the calc-1 gene that is also known as crustacean cardioactive peptide (CCAP or CCP1). Katacalcin exhibits immunomodulatory activity. Katacalcin activates PKA and decreases intracellular Ca2+ levels, inducing migration of CD14+ peripheral blood mononuclear cells and deactivating chemotaxis. Katacalcin may be used as a bio
Marker
for medullary thyroid tumors. Additionally, this peptide may play a role in signaling cascade elicited by treatments for mood disorders, such as antipsychotic medications.
Product Info
Cas No.
85916-47-8
Purity
≥95%
Formula
C
97
H
154
N
34
O
36
S
2
Formula Wt.
2436.64
Synonym
CCAP, CCP I, Calcitonin carboxyl-terminal flanking peptide
Appearance
White to off white powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
K0276 Info Sheet PDF
References
Kaneider NC, Egger P, Wiedermann FJ, et al. Involvement of cyclic adenosine monophosphate-dependent protein kinase A and pertussis toxin-sensitive G proteins in the migratory response of human CD14+ mononuclear cells to katacalcin. J Bone Miner Res. 2002 Oct;17(10):1872-82. PMID: 12369791.
Angelucci F, Gruber SH, Mathé AA. A pilot study of rat brain regional distribution of calcitonin, katacalcin and calcitonin gene-related peptide before and after antipsychotic treatment. Neuropeptides. 2001 Oct-Dec;35(5-6):285-91. PMID: 12030813.
Blind E, Raue F, Klaiber T, et al. Evaluation of sensitive PDN-21 (katacalcin) determination as tumor
Marker
in medullary thyroid carcinoma. J Endocrinol Invest. 1992 Feb;15(2):93-8. PMID: 1569295.