商品编号


AG-40A-0150-C010



品牌


Adipogen



公司


Adipogen



公司分类


Proteins



Size

10 ?g


商品信息


More Information



Product Details



Synonyms

Glutathione Peroxidase 1; Cellular Glutathione Peroxidase; GPx-1; GSHPx-1



Product Type

Protein



Properties



Source/Host

E. coli



Sequence

Human GPX1 (aa 1-201) is fused at the C-terminus to a His-tag.



Crossreactivity

Human



BIOLOG
ical Activity


Catalytic activity:
2 Glutathione + H
2
O
2
→ Glutathione Disulfide + 2 H
2
O. Not tested.



MW

~25kDa (SDS-PAGE)



Purity

≥90% (SDS-PAGE)



Endotoxin Content

<1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">1eu>



Reconstitution

Reconstitute with water.



Formulation

Lyophilized from 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl, 1mM DTT.



Other Product Data

Uniprot link P07203: GPX1 (human)



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
For maximum product recovery after thawing, centrifuge the vial before opening the cap.



Use/St
ABI
lity

Working aliquots are stable for up to 3 months when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


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Glutathione peroxidase 1 (GPX1) is an antioxidant enzyme that is down-regulated in cancer cells. Protects the hemoglobin in erythrocytes from oxidative breakdown. Its main role is the prevention of cancer initiation by ROS-mediated DNA damage.