商品编号


CHI-HF-22017A-C050



品牌


Adipogen



公司


Adipogen



公司分类


Proteins



Size

50 ?g

商品信息


More Information



Product Details



Synonyms

Interleukin-17A; Cytotoxic T-lymphocyte-associated Antigen 8; CTLA-8



Product Type

Protein



Properties



Source/Host

HEK 293 cells



Sequence

The extracellular domain of human IL-17A (aa 20-155) is fused to the N-terminus of the Fc region of mutant human IgG1.



Crossreactivity

Human



BIOLOG
ical Activity

Measured by its
ABI
lity to induce IL-6 secretion.



MW

~42kDa (SDS-PAGE)



Purity

≥98% (SDS-PAGE)



Endotoxin Content

<5eu g="" purified="" protein="" (lal="" test;="" lonza).="">5eu>



Reconstitution

Reconstitute 50?g vial with 50 ?l sterile water to a concentration of 1mg/ml.
Add 1X PBS to the desired protein concentration.



Formulation

Lyophilized from 0.2μm-filtered solution in PBS.



Other Product Data

NCBI reference AAH67505.1: IL-17A (human)



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.



Use/St
ABI
lity

Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


Download PDF





Interleukin-17A (IL-17A) exhibits multiple
BIOLOG
ical activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblsts, the enhancement of surface expression of ICAM-1 in fibroblast, activation of NF-κB and costimulation of T cell proliferation. Induces stromal cells to produce proinflammatory and hematopoietic cytokines.