商品编号


AG-40B-0024-C050



品牌


Adipogen



公司


Adipogen



公司分类


Proteins



Size

50 ?g


商品信息


More Information



Product Details



Synonyms

IL-1 Receptor Type I; Interleukin-1 Receptor Type I; RI; Interleukin-1 Receptor α CD121a; CD121 Antigen-like Family Member A



Product Type

Protein



Properties



Source/Host

HEK 293 cells



Sequence

Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.



Crossreactivity

Human



Specificity

Binds to?human IL-1β.



BIOLOG
ical Activity

Blocks IL-1β activity.



MW

~80kDa (SDS-PAGE)



Purity

≥95% (SDS-PAGE)



Endotoxin Content

<0.1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.1eu>



Concentration

1mg/ml after reconstitution.



Reconstitution

Reconstitute with 50μl sterile water.



Formulation

Lyophilized. Contains PBS.



Other Product Data

UniProt link P14778: IL-1 Receptor Type I (human)



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
PBS containing at least 0.1% BSA should be used for further dilutions.



Use/St
ABI
lity

Stable for at least 6 months after receipt when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


Download PDF





IL-1RI is the receptor for interleukin-1α (IL-1A), β (IL-1B) and interleukin-1 receptor antago
NIST
protein (IL-1RA). Binding to the ago
NIST
leads to the activation of NF-κB. Signaling involves formation of a ternary complex containing IL1RAP, le
ADI
ng the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.