商品编号


AG-40B-6001-C010



品牌


Adipogen



公司


Adipogen



公司分类


Proteins



Size

10 ?g


商品信息


More Information



Product Details



Synonyms

LCN2; Siderocalin; Oncogene 24p3; Neutrophil Gelatinase-associated Lipocalin; NGAL



Product Type

Protein



Properties



Source/Host

E. coli



Sequence

Human lipocalin-2 (aa 21-198) is fused at the N-terminus to a linker and a His-tag.



Crossreactivity

Human



MW

~25kDa (SDS-PAGE)



Purity

≥90% (SDS-PAGE)



Concentration

1mg/ml



Formulation

Liquid. 0.2μm-filtered solution in 20mM Tris-HCl, pH8 containing 10% glycerol, 1mM DTT and 50mM NaCl.



Other Product Data

UniProt link P80188: Lipocalin-2 (human)



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

Avoid freeze/thaw cycles.



Use/St
ABI
lity

Stable for at least 6 months after receipt when stored at -20°C.



Documents



MSD
S


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Product Specification Sheet



Datasheet


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Lipocalin-2 [LCN2, NGAL] is an iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. The binding bacterial siderophores is important in the innate immune response to bacterial infection. Upon encountering inv
ADI
ng bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of LCN2. Secreted LCN2 then limits bacterial growth by sequestering iron-containing siderophores. LCN2 is expressed in neutrophils and in low levels in the kidney, prostate and epithelia of the respiratory and alimentary tracts. It is used as a bio
Marker
of kidney injury.