商品编号


AG-40T-0309-C050



品牌


Adipogen



公司


Adipogen



公司分类


Proteins



Size

50 ?g

商品信息


More Information



Product Details



Synonyms

OTU Domain-containing Protein 7B; Cellular Zinc Finger anti-NF-κ-B Protein; Zinc Finger A20 Domain-containing Protein 1; ZA20D1



Product Type

Protein



Properties



Source/Host

E. coli



Sequence

Human OTUD7B (catalytic domain, including the OTU domain aa 167-440) (Accession Nr. Q6GQQ9).



Crossreactivity

Human



Formulation

Liquid. In 50mM HEPES pH 7.5, 100mM NaCl, 10% Glycerol (v/v), 1mM TCEP.



Other Product Data


Use:
Ubiquitin-specific deconjugating enzyme. Reaction conditions will need to be optimized for each specific application. We recommend an initial protein concentration of 0.1-1?M.



Declaration

Manufactured by Boston Biochem



Shipping and Handling



Shipping

DRY ICE



Short Term Storage

-20°C



Long Term Storage

-80°C



Handling Advice

Aliquot to avoid freeze/thaw cycles.



Use/St
ABI
lity

Stable for at least 1 year after receipt when stored at -80°C.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


Download PDF





OTU domain-containing protein 7B (OTUD7B), also known as Cezanne, is a C64 type peptidase and a member of the ovarian tumor (OTU) protein super-family with a predicted molecular weight of 93 kDa. The human protein shares 90% amino acid sequence identity with its mouse ortholog. Cezanne has been reported to cleave K48-, and K63-linked poly-ubiquitin chains and also to display a preference for K11-linked chains. It has been shown to play a role in the negative regulation of NF-κB signaling, poss
IBL
y by deubiquitination of RIPK1 and TRAF3.