商品编号


AG-40A-0011-C050



品牌


Adipogen



公司


Adipogen



公司分类


Proteins



Size

50 ?g


商品信息


More Information



Product Details



Synonyms

FIZZ3; Found in Inflammatory Zone 3; ADSF;
ADI
pose Tissue-Specific Secretory Factor



Product Type

Protein



Properties



Source/Host

HEK 293 cells



Sequence

Mouse resistin (aa 21-114) is fused at the N-terminus to a FLAG
?
-tag.



Crossreactivity

Mouse



Application

Has been shown to be a fully-functional ligand for decorin [1].



MW

~15kDa (SDS-PAGE)



Purity

≥90% (SDS-PAGE)



Endotoxin Content

<0.1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.1eu>



Concentration

0.4mg/ml



Formulation

Liquid. 0.2μm-filtered solution in PBS, pH 7.2.



Other Product Data


UniProt link Q99P87: Resistin (mouse) (precursor)

FLAG is a registered trademark of
Sigma-Aldrich
Co.




Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.



Use/St
ABI
lity

Working aliquots are stable for up to 3 months when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


Download PDF





The
ADI
pocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELM-α/FIZZ 1 and RELM-β/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits
ADI
pogen
esis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an
ADI
pocyte-secreted factor thought to link obesity and T2DM.


Product References

An Isoform of Decorin Is a Resistin Receptor on the Surface of
ADI
pose
Progen
itor Cells: A.C. Daquinag, et al.; Cell Stem Cell
9,
74 (2011)