商品编号


C1400



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


E2 Conjugating Enzymes



Size

25 ?g


商品信息

Ube2D1 is an E2 enzyme, which is part of the E1, E2, and E3 cascade respons
IBL
e for ubiquitination of protein substrates. Two other homologues of Ube2D1 exist called Ube2D2 and Ube2D3. Ube2D2 is 89% identical to the amino acid sequence of Ube2D1 ad Ube2D3 is 88% identical. Ube2D1 has been linked to cadminum toxicity. It might also play a role in LDL cholesterol receptor ubiquitination in an Idol-dependent fashion.

Additional Information






Product Name:

6xHis-Ube2D1 (UbcH5A)



Also Known As:

USFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1



Catalog No.:

C1400



Size:

25 ?g



Molecular Weight:

16.6 kDa



Species:

Human



Source:

Bacterial recombinant



Stock:

20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol



Concentration:

See tube label



Quality Assurance:

~95% by SDS-PAGE, see datasheet for gel image



Storage:

Store at -80°C; avoid multiple freeze-thaw cycles



PDF Data Sheet:

PDF Datasheet
，
MSD
S



NCBI RefSeq:

NM_003338



Image(s):

(Click image to enlarge)








Coomassie-stained SDS-PAGE
Lane 1: Molecular weight
Marker
s
Lane 2: 5 ?g purified 6xHis-Ube2D1 (UbcH5A)







Shipping Method:

Dry ice shipping



References:

1. Scheffner M,
et al
. (1994) Proc Natl Acad Sci USA 91, 8797–8801.
2. Huibregtse JM,
et al
. (1995) Proc Natl Acad Sci USA 92(7), 2563 – 2567. 3. Gehrke SG,
et al
. (2003) Blood 101, 3288 – 3293.
4. Tokumoto M,
et al
. (2011) J Toxicol Sci 36(2), 191 – 200.




Details

Ube2D1 is an E2 enzyme, which is part of the E1, E2, and E3 cascade respons
IBL
e for ubiquitination of protein substrates. Two other homologues of Ube2D1 exist called Ube2D2 and Ube2D3. Ube2D2 is 89% identical to the amino acid sequence of Ube2D1 ad Ube2D3 is 88% identical. Ube2D1 has been linked to cadminum toxicity. It might also play a role in LDL cholesterol receptor ubiquitination in an Idol-dependent fashion.

Images:
(Click image to enlarge)








Coomassie-stained SDS-PAGE
Lane 1: Molecular weight
Marker
s
Lane 2: 5 ?g purified 6xHis-Ube2D1 (UbcH5A)