商品编号


C2800



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


E2 Conjugating Enzymes



Size

25 ?g


商品信息

Ube2K (or E2-25K) is an E2 enzyme, which is part of the E1, E2, and E3 cascade respons
IBL
e for ubiquitination of protein substrates. It contains a C-terminal UBA domain and an E2 catalytic domain. Ube2K contains a 47 amino acid residue tail that contributes greatly to its specific characteristics. Ube2K is one of the E2s that are capable of forming K48-linked polyubiquitin chains.

Additional Information






Product Name:

GST-Ube2K (E2-25K)



Also Known As:

LIG; HIP2; HYPG; UBC1; E2-25K; DKFZp564C1216; DKFZp686J24237



Catalog No.:

C2800



Size:

25 ?g



Molecular Weight:

22.4 kDa



Species:

Human



Source:

Bacterial recombinant



Stock:

20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol



Concentration:

See tube label



Quality Assurance:

~90% by SDS-PAGE, see datasheet for gel image



Storage:

Store at -80°C; avoid multiple freeze-thaw cycles



PDF Data Sheet:

PDF Datasheet
，
MSD
S



NCBI RefSeq:

NM_005339



Image(s):

(Click image to enlarge)








Coomassie-stained SDS-PAGE
Lane 1: Molecular weight
Marker
s
Lane 2: 5 ?g purified GST-Ube2K (E2-25K)







Shipping Method:

Dry ice shipping



References:

1. Kalchman MA,
et al
. (1996) J Biol Chem 271, 19385 – 19394.
2. Haldeman MT,
et al
. (1997) Biochemistry 36(34), 10526 – 10537. 3. Yao T,
et al
. (2000) J Biol Chem 275, 36862–36868.




Details

Ube2K (or E2-25K) is an E2 enzyme, which is part of the E1, E2, and E3 cascade respons
IBL
e for ubiquitination of protein substrates. It contains a C-terminal UBA domain and an E2 catalytic domain. Ube2K contains a 47 amino acid residue tail that contributes greatly to its specific characteristics. Ube2K is one of the E2s that are capable of forming K48-linked polyubiquitin chains.

Images:
(Click image to enlarge)








Coomassie-stained SDS-PAGE
Lane 1: Molecular weight
Marker
s
Lane 2: 5 ?g purified GST-Ube2K (E2-25K)