商品编号


20801-2.5KG



品牌


西格玛奥德里奇(Sigma-Aldrich)



公司


Merck & Co., Inc.



公司分类


Analytical/Chromatography



Size

2.5KG


商品信息

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Synonym:

β,β,β-Trichloro-
tert
-butyl alcohol hemihydrate, ‘Acetone chloroform’, ‘Chlorobutanol’

CAS Number
6001-64-5



Linear Formula
Cl
3
CC(CH
3
)
2
OH · 0.5H
2
O



Molecular Weight
186.46



?Beilstein Registry Number
878167



?EC Number
249-042-3



?MDL number
MFCD02179352



?PubChem Substance ID
57647873


Properties:

Related Categories

Analytical/Chromatography, Pharmacopoeia, Pharmacopoeia A-Z
Description:
Application

1,1,1-Trichloro-2-methyl-
2-propanol hemihydrate (chlorobutanol) is a preservative used as a standard for quantifying preservatives in pharmaceutical formulations by using capillary electrophoretic method.
It has also been used to anesthetize leeches for preparing c-DNA library from regenerating retzius cells.


Biochem/physiol Actions

Chlorobutanol or 1,1,1-Trichloro-2-methyl-
2-propanol is a opthalmic preservative and sedative hypnotic that possess antibacterial and antifungal properties.
It also decreases the conduction velocity and induces conduction failure and automaticity within isolated ventricular muscle strips as well as impacts myocardial cells by acting on cell membrane and reduces isometric tension produced by heart.

Safety:

Symbol?


??GHS07



Signal word?


Warning




Hazard statements?

H302



Precautionary statements?

P301 + P312 + P330



Personal Protective Equipment?

dust mask type N95 (US), Eyeshields, Gloves



RIDADR?

NONH for all modes of transport



WGK Germany?

3



Flash Point(F)?

212?°F



Flash Point(C)?

100?°C