商品编号


F20204AB



品牌


FormuMax



公司


FormuMax Scientific Inc



公司分类


Ammonium Gradient Liposomes for Active Loading



Size

10 mL

商品信息

HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3)
liposomes
with Ammonium Sulfate Gr
ADI
ent (100nm)

HSPC/CHOL/mPEG2000-DSPE (56.2/38.5/5.3 mol/mol)
liposomes
? with ammonium gr
ADI
ent is the original lipid copmposition used for the commercial product Doxil(R) (STEALTH
Liposoma
l doxorubicin HCl). This lipid composition is a formulator's choice in pharmaceutical/biotech industry for both formulation feasibility studies and
Liposoma
l product development.?HSPC is essentially equivalent to DSPC (HSPC contains?about 85 % DSPC?and 15% DPPC). The main advantages for using HSPC are its lower cost and avail
ABI
lity of GMP quality raw materials. HSPC material used at
FormuMax
is? from one of the world’s premier lipid suppliers.?

This
liposomes
has the same lipid composition as used in the commercial STEALTH
liposomes
,
DOXIL
?

(doxorubicin HCl liposome injection). Note the larger liposome particle size of 100nm compared to 85nm for Doxil
?
. If you want an ammomium liposmes more comparable to
Doxil
?, please see?
F20204AS.?

?

Specifications

Product code:
F20204AB

Lipid composition:
HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol)

Mean particle size:
100 nm (95 - 120 nm)

Lipid concentration
: 60?(60 -70mM)

Hydration buffer (lo
ADI
ng battery):?
250 mM ammonium sulfate

External solution:
?10% sucrose, 20mM sodium PO4, pH 6.5 ± 0.2

Shelf-life:
?6 months

Storage:
?2-8?°C, do not freeze

?

HSPC:
hydrogenated phosphatidylcholine (Soy)

CHOL:
cholesterol

mPEG2000-DSPE:
18:0 PEG2000 PE:1,2-distearoyl-
sn
-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

?