商品编号


F30204-IT



品牌


FormuMax



公司


FormuMax Scientific Inc



公司分类


Drug Loaded Liposomes



Size

2 mL

商品信息

PEGylated
Liposoma
l Irinotecan HCl

Irinotecan HCl is loaded into PEGylated
liposomes
composed of HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) with ammonium gr
ADI
ent by the active lo
ADI
ng approach. The
liposomes
are produced by the extrusion method. The product is of?high quality with?narrow particle size distribution and high drug encapsualtion efficiency.?

?

Product For Research only and NOT for Human Use

Specifications

Product code: F30204S-IT

Lipid composition:
? HSPC/CHOL/mPEG2000-DSPE (
50:45:5
?mol/mol)

Lipid concentration
: ?20.0 mM

Iroinotecan
HCl:
? 2.0 mg/mL

Encapsulation efficiency:
> 95% (typically 98%)

Lo
ADI
ng battery:?
250 mM?ammonium sulfate

Mean particle size:
??
100 nm (80-110 nm)

External solution:
? 10% sucrose, 20 Mm HEPES, pH 7.0

Shelf-life:
?3 months, storage:?2-8 degree C

?

Irinotecan:
?Synonym:
(
S
)?-?4,11-?diethyl-?3,4,12,14-?tetrahydro-?4-?hydroxy-?3,14-?dioxo-?1H-?pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester, CPT-11, [1,4′-Bipiperidine]-1′-carboxylic acid?

CAS Number 100286-90-6,?Empirical Formula: C
33
H
38
N
4
O
6
· HCl, Sigma Cat#?I1406

HSPC:
hydrogenated phosphatidylcholine (Soy)

CHOL:
cholesterol

mPEG2000-DSPE:
18:0 PEG2000 PE:1,2-distearoyl-
sn
-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]