商品编号


4890-25-K



品牌


Trevigen



公司


Trevigen, Inc



公司分类


Apoptosis



Size

2500 Wells, 5000 Wells

商品信息

Description

Changes in cell proliferative activity caused by trophic factors, growth inhibitors, or inducers and inhibitors of apoptosis, may be quantified using the MTT-CPA. MTT is reduced to an insoluble formazan dye by mitochondrial enzymes associated with metabolic activity. The reduction of MTT is primarily due to glycolytic activity within the cell and is dependent upon the presence of NADH and NADPH. The resultant intracellular purple formazan can be solubilized and quantitated by spectroscopic means.

Features:


Allows measurement of proliferation rate, and conversely, the reduction in cell vi
ABI
lity.

Minimizes the number of steps necessary to complete the assay and interpret the data.

Yields low background absorbance values in the absence of cells.

Accurate quantification of changes in cell proliferation due to the linear relationship between cell number and signal produced for each cell type.

Stable when stored at 4°C.





Catalog # 4890-50-K includes :



Catalog Number

Description

Qty



4890-25-01

MTT Reagent

2



4890-25-02

Detergent Reagent

2







Catalog # 4890-25-K includes :



Catalog Number

Description

Qty



4890-25-01

MTT Reagent

1



4890-25-02

Detergent Reagent

1




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Identification of Chemical Compounds That Inhibit the Function of Glutamyl-tRNA Synthetase from Pseudomonas aeruginosa
Yanmei Hu, Edgar Guerrero, Megan Keniry, Joel Manrrique, and James M. Bullard
J Biomol Screen, Jun 2015; 10.1177/1087057115591120.
http://jbx.sagepub.com/cgi/content/abstract/1087057115591120v1

Characterization of CM572, a Selective Irrevers
IBL
e Partial Ago
NIST
of the Sigma-2 Receptor with Antitumor Activity
Hilary Nicholson, Anthony Comeau, Christophe Mesangeau, Christopher R. McCurdy, and Wayne D. Bowen
J. Pharmacol. Exp. Ther., Jul 2015; 354: 203 – 212.
http://jpet.aspetjournals.org/cgi/content/abstract/354/2/203

“Imidazolium Salts as Small-Molecule Urinary Bladder Exfoliants in a
Murine Model”
“Patrick O. Wagers, Kristin M. Tiemann, Kerri L. Shelton, William G. Kofron, Matthew J. Panzner, Karen L.
Wooley, Wiley J. Youngs, and David A. Hunstad”
Antimicrob. Agents Chemother., Sep 2015; 59: 5494 – 5502
http://aac.asm.org/cgi/content/abstract/59/9/5494

“Identification of Chemical Compounds That Inhibit the Function of Glutamyl-tRNA Synthetase from Pseudomonas aeruginosa”
Yanmei Hu, Edgar Guerrero, Megan Keniry, Joel Manrrique, and James M. Bullard
J Biomol Screen, Oct 2015; 20: 1160 – 1170.
http://jbx.sagepub.com/cgi/content/abstract/20/9/1160