商品编号


SC022-RB



品牌


Gentarget



公司


Gentarget



公司分类


Ion Channel cells




1 Ea

商品信息


Transformed from
HEK293 cells
by lentiviral system with?sequence verified?human CFTR gene (
NM_000492
).?

CFTR
?
was?constitutively expressed?under an enhanced EF1a?promoter.?The
RFP-Blasticidin

Marker
was expressed under Rsv promoter. The cell constitutively express both
CFTR
and
RFP
.

This CFTR protein involved in multi-drug resistance. It belongs to a ATP-binding cassette (ABC) subfamily. The ABC proteins transport various molecules across extra- and intra-cellular membranes. The CFTR functions as a chloride channel and controls the regulation of other transport pathways. It is characterized in chronic bronchopulmonary disease (with recurrent respiratory infections), pancreatic insufficiency (which leads to malabsorption and growth retardation) and elevated sweat electrolytes. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. ?

Please see details?in?
Product Manual
.

Sold at:? 1 vial x (2?x 10
6
cells)/vial
?

Cat# SC022-RB