商品编号


3400-010-03



品牌


Trevigen



公司


Trevigen, Inc



公司分类


Organoid and Stem Cell Research



Size

1 ml

商品信息

Description

Cultrex? Mouse?Laminin I is purified from Engelbreth-Holm-Swarm (EHS) tumor. Laminin I is a major component of the basement membrane which is a continuous sheet of specialized extracellular matrix that forms an interface between endothelial, epithelial, muscle, or neuronal cells and their adjacent stroma and that plays an essential role in tissue organization by influencing cell adhesion, migration, proliferation, and differentiation.?This highly purified preparation of mouse Laminin I is composed of α1β1γ1 chains with a total MW of 800 KDa.

Cultrex? Stem Cell Qualified Mouse?Laminin I is a purified basement membrane protein that has been developed, produced and qualified for attachment and maintenance?of embryonic and induc
IBL
e pluripotent stem cells.

Quality control specifications:


Mouse colonies are routinely screened for pathogens using?mouse antibody production (MAP) testing.

Engelbreth-Holm-Swarm (EHS) tumor is LDEV-free.

No bacterial or fungal growth detected after incubation at 37°C for 14 days following
USP
sterility testing guidelines.

Endotoxin concentration ≤ 20 EU/ml by Limulus Amoebocyte Lysate (LAL) assay.

Protein concentration of 1 mg/ml.

No mycoplasma contamination detected by PCR.

Provided in Dulbecco’s Modified Eagle’s medium (DMEM) without phenol red.

Purity?≥90% (SDS-PAGE).

BIOLOG
ical activity determined for each lot:

Promotes the attachment of human iPSCs.

Effectively maintains human iPSCs in a pluripotent state in a feeder-free culture.




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