商品编号


U1100



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Apoptosis / Necrosis



Size

50 ?g


商品信息

TRAIL (TNF-related apoptosis-inducing ligand) is a cytokine that is produced and secreted by most normal tissue cells. TRAIL binds to cell surface death receptors DR4 and DR5, by which it activates caspase-8 to induce apoptosis of cancer cells but not of normal cells. This product contains the extracellular domain (amino acids 95-281) of full-length human TRAIL and it is competent for binding of DR4 and DR5. This product has been tested for inducing apoptosis of TRAIL-sensitive cancer cell lines at concentrations of 1-50 ng/mL.

Additional Information






Product Name:

6xHis-TRAIL



Also Known As:

TNFSF10; TL2; APO2L; CD253; Apo-2L



Catalog No.:

U1100



Size:

50 ?g



Molecular Weight:

32.5 kDa



Species:

Human



Source:

Bacterial recombinant



Stock:

20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol



Concentration:

See tube label



Quality Assurance:

~ 85% by SDS-PAGE



Storage:

Store at -80°C; avoid multiple freeze-thaw cycles



PDF Data Sheet:

PDF Datasheet



NCBI RefSeq:

NM_003810.3



Image(s):

(Click image to enlarge)








Coomassie-stained SDS-PAGE
Lane 1: Molecular weight
Marker
s
Lane 2: 5 ?g purified 6xHis-TRAIL







Shipping Method:

Dry ice shipping



References:

N/A




Details

TRAIL (TNF-related apoptosis-inducing ligand) is a cytokine that is produced and secreted by most normal tissue cells. TRAIL binds to cell surface death receptors DR4 and DR5, by which it activates caspase-8 to induce apoptosis of cancer cells but not of normal cells. This product contains the extracellular domain (amino acids 95-281) of full-length human TRAIL and it is competent for binding of DR4 and DR5. This product has been tested for inducing apoptosis of TRAIL-sensitive cancer cell lines at concentrations of 1-50 ng/mL.

Images:
(Click image to enlarge)








Coomassie-stained SDS-PAGE
Lane 1: Molecular weight
Marker
s
Lane 2: 5 ?g purified 6xHis-TRAIL