商品编号


3520M-2H



品牌


Mabtech



公司


Mabtech



公司分类


NHP



Size

for 4 plates














商品信息
Basic ELISpot kit for enumeration of cells secreting IL-17A
The monkey IL-17A ELISpot kit is ideal for users who want the flexibility of setting up their own assay. The kit enables enumeration of cells secreting monkey IL-17A, and contains a matched pair of monoclonal capture and detection antibodies and Streptavidin-HRP.
The monoclonal antibodies in this kit react with human IL-17A and cross-react with IL-17A from non-human primates. See the Human/NHP cross-reactivity table.
Monkey IL-17A ELISpot kits are also available with Streptavidin-ALP. See Related products.
As complementary products, we offer ELISpot plates and substrates. See Related products.

Analyte Information

IL-17A
Interleukin-17A (IL-17A, IL17A) is a potent proinflammatory cytokine produced by activated Th17 (T-helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has been shown to also be produced by activated CD8+ T cells and γδ T cells. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce expression of cytokines, chemokines and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production and activation of T cells. Increased expression of IL-17A is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also associated with asthma, psoriasis, cancer and transplant rejection.
Application:


ELISpot


Reactivity:


NHP




Contents:


Capture mAb (MT241)
Biotinylated detection mAb (MT504)
Streptavidin-HRP


Size:

for 4 plates

Other formats:

Click to view all NHP IL-17Aproducts

Save time and reduce vari
ABI
lity with the
complete
and pre-coated ELISpot
PLUS
kit





I have compared
Mabtech
ELISpot assay to ELISpot assays we run at our company on regular basis "head-to-head" using identical samples.
Mabtech
's kits proved to be superior
to our protocol, had significantly lower background and provided better and higher detection of spots.








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Mabtech/Monkey IL-17A ELISpot
BASIC
(HRP)/3520M-2H/for 4 plates






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