商品编号


T3099-5 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

5 mg

商品信息

Product ID
T3099
Cas No.
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Thymic factor (thymulin) is an endogenous peptide that modulates immune and neuroendocrine signaling pathways. Thymic factor induces immunoneutralization and decreases secretion of prolactin and growth hormone (GH). In animal models of experimental autoimmune encephalitis (EAE), thymic factor prevents activation of p38 MAPK and NF-κB and release of pro-inflammatory cytokines, decreasing overall disease severity.
Product Info
Purity
≥95%
Formula
C
33
H
57
N
13
O
15
Formula Wt.
875.9
Synonym
Thymulin, Thymic factor, FTS
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
T3099 Info Sheet PDF
References
Martines EV, Reggiani PC, Camihort G, et al. The thymulin-lactotropic axis in rodents: thymectomy, immunoneutralization and gene transfer studies. Neuroimmunomodulation. 2013;20(5):256-63. PMID: 23941809.
Lunin SM, Glushkova OV, Khrenov MO, et al. Thymic peptides restrain the inflammatory response in mice with experimental autoimmune encephalomyelitis. Immuno
BIOLOG
y. 2013 Mar;218(3):402-7. PMID: 22727332.
Reggiani PC, Martines EV, Camihort GA, et al. Role of thymulin on the somatotropic axis in vivo. Life Sci. 2012 Sep 4;91(5-6):166-71. PMID: 22781709.
Santos M, Henriques-Coelho T, Leite-Moreira A. Immunomodulatory role of thymulin in lung diseases. Expert Opin Ther Targets. 2010 Feb;14(2):131-41. PMID: 20055713.
Goya RG, Bolognani F. Homeostasis, thymic hormones and aging. Gerontology. 1999 May-Jun;45(3):174-8. PMID: 10202264.