商品编号


O9497-1 g



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

1 g

商品信息

Product ID
O9497
Cas No.
50-56-6
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Oxytocin is an endogenous peptide neurohormone that does not cross the blood-brain barrier. Oxytocin binds the oxytocin receptor (OXTR) and exhibits neuromodulatory, antinociceptive, antidepressant, anxiolytic, and other activities; it is involved with feelings of trust, memory, intimacy, and fidelity. Oxytocin also inhibits acid-sensing ion channels and may be used as a bio
Marker
of bone mineral density.
Product Info
Cas No.
50-56-6
Purity
≥95%
Formula
C
43
H
66
N
12
O
12
S
2
Formula Wt.
1007.2
Chemical Name
L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic (1-6)-disulfide
IUPAC Name
1-[19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-butan-2-yl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Synonym
Ocytocin; Interocine-S; Perlacton; Pitocin; Syntocinon; Orasthin; Oxystin; Partocon.
Melting Point
192-194°C
Solubility
Soluble in water, 1-butanol or 2-butanol.
Appearance
White to off-white powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
O9497 Info Sheet PDF
References
Breuil V, Panaia-Ferrari P, Fontas E, et al. Oxytocin, a new determinant of bone mineral density in post-menopausal women: analysis of the OPUS cohort. J Clin Endocrinol Metab. 2014 Apr;99(4):E634-41. PMID: 24446658.
Yuen KW, Garner JP, Carson DS, et al. Plasma oxytocin concentrations are lower in depressed vs. healthy control women and are independent of cortisol. J Psychiatr Res. 2014 Apr;51:30-6. PMID: 24405552.
Qiu F, Qiu CY, Cai H, et al. Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin-1a receptor in primary sensory neurons. Br J Pharmacol. 2014 Feb 15. [Epub ahead of print]. PMID: 24641084.
Evans SL, Dal Monte O, Noble P, et al. Intranasal oxytocin effects on social cognition: A critique. Brain Res. 2013 Nov 14. [Epub ahead of print]. PMID: 24239931.