商品编号


G6000-1 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

1 mg

商品信息

Product ID
G6000
Cas No.
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Glycoprotein 38 (gp38) is a transmembrane O-glycoprotein that maintains barrier function in high endothelial venules. In development, gp38 activates platelets to induce separation of lymphatic and blood vascular systems. Additionally, gp38 may exhibit carcinogenic/tum
Origen
ic activity, as it promotes cell motility via PKA signaling and is used as a bio
Marker
to detect various cancers.
Product Info
Purity
≥95%
Formula
C
133
H
209
N
41
O
38
S
2
Formula Wt.
3054.53
Synonym
Podoplanin; gp38
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
G6000 Info Sheet PDF
References
Herzog BH, Fu J, Wilson SJ, et al. Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2. Nature. 2013 Oct 3;502(7469):105-9. PMID: 23995678.
Krishnan H, Ochoa-Alvarez JA, Shen Y, et al. Serines in the intracellular tail of podoplanin (PDPN) regulate cell motility. J Biol Chem. 2013 Apr 26;288(17):12215-21. PMID: 23530051.
Konishi S, Yasuchika K, Ishii T, et al. A transmembrane glycoprotein, gp38, is a novel
Marker
for immature hepatic
Progen
itor cells in fetal mouse livers. In Vitro Cell Dev Biol Anim. 2011 Jan;47(1):45-53. PMID: 21104040.
Uhrin P, Zaujec J, Breuss JM, et al. Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation. Blood. 2010 May 13;115(19):3997-4005. PMID: 20110424.