商品编号


F5870-5 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

5 mg

商品信息

Product ID
F5870
Cas No.
59880-97-6
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
N-fMLF is a peptide that binds n-formyl peptide receptors (FPRs) on neutrophils, playing a role in neutrophil activation. This peptide activates NADPH oxidase-dependent respiratory burst in neutrophils, generating ROS and inflammatory signaling cascades.
Product Info
Cas No.
59880-97-6
Purity
≥95%
Formula
C
21
H
31
N
3
O
5
S
Formula Wt.
437.6
IUPAC Name
2-[[2-[(2-formamido-4-methylsulfanylbutanoyl)amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid
Synonym
N-Formylmethionine leucyl-phenylalanine; L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)-; Tyramine HCl; N-Formyl-Met-Leu-Phe
Appearance
White to off white powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
F5870 Info Sheet PDF
References
Hurtado-Nedelec M, Makni-Maalej K, Gougerot-Pocidalo MA, et al. Assessment of priming of the human neutrophil respiratory burst. Methods Mol Biol. 2014;1124:405-12. PMID: 24504964.
Andréasson E, ?nnheim K, Forsman H. The subcellular localization of the receptor for platelet-activating factor in neutrophils affects signaling and activation characteristics. Clin Dev Immunol. 2013;2013:456407. PMID: 24069041.
Sengel?v H, Boulay F, Kjeldsen L, et al. Subcellular localization and translocation of the receptor for N-formylmethionyl-leucyl-phenylalanine in human neutrophils. Biochem J. 1994 Apr 15;299 ( Pt 2):473-9. PMID: 8172608.