商品编号


L0250-1 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

1 mg

商品信息

Product ID
L0250
Cas No.
Purity
≥98%
Description
Product Info
Shipping and Storage
Downloads
References

Description
This hexapeptide is equivalent to a sequence found on the A1 chain of laminin; it exhibits pro-angiogenic activity. Like other laminin peptides, this sequence can be used in combination with chemotherapeutics to deliver the drug to target tumor tissues. In vitro, this peptide increases vessel formation and migration. This peptide also increases secretion of matrix metalloproteinases 2 and 9 (MMP2/9), modulating the morphology of salivary gland adenoid cystic carcinoma cells.
Product Info
Purity
≥98%
Formula
C
82
H
148
N
31
O
26
S
Formula Wt.
2016.30
Synonym
Laminin A Chain (2091-2108)
Appearance
White Powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
L0250 Info Sheet PDF
References
Stevenson M, Hale AB, Hale SJ, et al. Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via alpha6-integrins. Cancer Gene Ther. 2007 Apr;14(4):335-45. PMID: 17235355.
Freitas VM, Scheremeta B, Hoffman MP, et al. Laminin-1 and SIKVAV a laminin-1-derived peptide, regulate the morphology and protease activity of a human salivary gland adenoid cystic carcinoma cell line. Oral Oncol. 2004 May;40(5):483-9. PMID: 15006619.
Kibbey MC, Corcoran ML, Wahl LM, et al. Laminin SIKVAV peptide-induced angiogenesis in vivo is potentiated by neutrophils. J Cell Physiol. 1994 Jul;160(1):185-93. PMID: 7517404.