商品编号


M1752-0.5 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

0.5 mg

商品信息

Product ID
M1752
Cas No.
135306-85-3
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Men 10376 is a peptide antago
NIST
at neurokinin-2 (NK2) receptors. Men 10376 decreases stretch-activated contractility in airway smooth muscle tissue ex vivo and inhibits OVA-induced bronchoconstriction in vivo.
Product Info
Cas No.
135306-85-3
Purity
≥95%
Formula
C
57
H
68
N
12
O
10
Formula Wt.
1081.25
IUPAC Name
3-amino-4-[[1-[[1-[[1-[[1-[[1-[(1,6-diamino-1-oxohexan-2-yl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Synonym
Neurokinin A(4-10), tyr(5)-trp(6,8,9)-lys(10)-
Appearance
White to off white powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
M1752 Info Sheet PDF
References
Hernandez JM, Cox G, Janssen LJ. Involvement of the neurokinin-2 receptor in airway smooth muscle stretch-activated contractions assessed in perfused intact bovine bronchial segments. J Pharmacol Exp Ther. 2008 Nov;327(2):503-10. PMID: 18719290.
Krishnakumar S, Holmes EP, Moore RM, et al. Non-adrenergic non-cholinergic excitatory innervation in the airways: role of neurokinin-2 receptors. Auton Autacoid Pharmacol. 2002 Aug;22(4):215-24. PMID: 12656947.