商品编号


M9643-1 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

1 mg

商品信息

Product ID
M9643
Cas No.
106128-98-7
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Myelin basic protein (1-11) is a peptide antigen fragment that may bind to receptors expressed by T cells involved in autoimmune diseases such as multiple sclerosis. Admi
NIST
ration of myelin basic protein (1-11) decreases expression of IL-12 in the lymph nodes of mice with experimental autoimmune encephalitis (EAE), an animal model of multiple sclerosis; IL-12 appears to play a protective role against EAE pathology and development.
Product Info
Cas No.
106128-98-7
Purity
≥95%
Formula
C
52
H
88
N
22
O
17
Formula Wt.
1293.42
IUPAC Name
N-Acetyl-L-alanyl-L-seryl-L-glutaminyl-L-lysyl-N5-(diaminomethylen)-L-ornithyl-L-prolyl-L-seryl-L-glutaminyl-N5-(diaminomethylen)-L-ornithyl-L-histidylglycin
Appearance
White to off white powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
M9643 Info Sheet PDF
References
Buenafe AC, Sherwood C, Moes N, et al. Recombinase-activating gene 1-associated expression of the myelin basic protein 1-11-specific transgenic T-cell receptor in H-2b mice. J Neurosci Res. 2009 Jan;87(1):42-9. PMID: 18752298.
Zhang GX, Xu H, Kishi M, et al. The role of IL-12 in the induction of intravenous tolerance in experimental autoimmune encephalomyelitis. J Immunol. 2002 Mar 1;168(5):2501-7. PMID: 11859144.