商品编号


YIF-LF-PA0102



品牌


Adipogen



公司


Adipogen



公司分类


Antibodies



Size

100 ?l

商品信息


More Information



Product Details



Synonyms

TTR; TBPA; ATTR; PALB; Prealbumin; Transthyretin



Product Type

Polyclonal Antibody



Properties



Immunogen/Antigen

Recombinant human protein purified from E. coli.



Application

Western Blot (1:2,000)
Immunoprecipitation (1 μl)



Crossreactivity

Human
Mouse
Rat



Formulation

Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.



Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.



Declaration

Manufactured by AbFrontier



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Use/St
ABI
lity

Stable for at least 1 year after receipt when stored at -20°C.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


Download PDF





Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition. Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.


Product References
1) Hamilton, J.A. and Benson, M.D. (2001) Cell. Mol. Life Sci. 58, 1491-1521. (General)
2) Shirahama, T. et al. (1982) Am. J. Path. 107, 41-50. (General)
3) Episkopou, V. et al. (1993) Proc. Nat. Acad. Sci. 90, 2375-2379. (General)
4) Saraiva, M.J.M. (1995) Hum. Mutat. 5, 191-196. (General)
5) Pfeffer, B. et al. (2004) Mol. Vis. 10, 23-30. (General)