商品编号


F5201



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Inhibitors



Size

25 mg

商品信息

Nutlin-3 is a potent and selective small chemical compound that binds murine double minutes (MDM2) and blocks the MDM2/p53 interaction, by which nutlin-3 functions to st
ABI
lize p53 and induces senescence in cancer cells that express wild type p53.

Additional Information






Product Name:

Nutlin-3



Also Known As:

N/A



Catalog No.:

F5201



Size:

25 mg



CAS:

675576-98-4



Formula:

C
30
H
30
Cl
2
N
4
O
4



Molecular Weight:

581.49 Da



Form:

Lyophilized powder



Quality Assurance:

>98% by HPLC and NMR



Source:

Synthetic



Storage:

Elig
IBL
e for room temperature shipping. Store at 2-8°C upon receiving



PDF Data Sheet:

Download PDF datasheet



Image(s):

N/A



Shipping Method:

Room temperature shipping



References:

1. Vassilev LT,
et al
. (2004). Science 303 (5659): 844–848.
2. Shangary S,
et al
. (2008). Annu Rev Pharmacol Toxicol. 49: 223–241.




Details

Nutlin-3 is a potent and selective small chemical compound that binds murine double minutes (MDM2) and blocks the MDM2/p53 interaction, by which nutlin-3 functions to st
ABI
lize p53 and induces senescence in cancer cells that express wild type p53.