商品编号


F6121



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Inhibitors



Size

50 mg

商品信息

Nocodazole is a microtubule inhibitor which revers
IBL
y binds tubulin and alters tubulin-associated GTP hydrolysis as well as microtubule dynamics. While nocodazole is used to study many aspects on microtubule function, it is most commonly used to synchronize cell cycling in culture. Nocodazole is also used to induce the formation of Golgi mi
NIST
acks in eukaryotic cells.


Additional Information






Product Name:

Nocodazole



Also Known As:

N-?[6-?(2-?thienylcarbonyl)-?1H-?benzimidazol-?2-?yl]-?methyl ester-?carbamic acid



Catalog No.:

F6121



Size:

50 mg



Molecular Weight:

301.32 Da



Species:

N/A



Source:

Synthetic



Stock:

Powder



Concentration:

N/A



Quality Assurance:

>99% by HPLC and NMR



Storage:

Elig
IBL
e for room temperature shipping. Store at -20°C upon receiving; protect from air and light



PDF Data Sheet:

PDF Datasheet



NCBI RefSeq:

N/A



Image(s):

N/A



Shipping Method:

Room temperature shipping



References:

1. Vasquez RJ,
et al
. (1997) Mol.Biol.Cell 8(6):973-85.
2. Mikhailov A,
et al
. (1998) Cell.Motil.
Cytoskeleton
41(4):325-40.
3. Webb JL,
et al
. (2004) Int.J.Biochem.Cell Biol. 36(12):2541-50.
4. Mizushima N,
et al
. (2010) Cell 140(3):313-26




Details

Nocodazole is a microtubule inhibitor which revers
IBL
y binds tubulin and alters tubulin-associated GTP hydrolysis as well as microtubule dynamics. While nocodazole is used to study many aspects on microtubule function, it is most commonly used to synchronize cell cycling in culture. Nocodazole is also used to induce the formation of Golgi mi
NIST
acks in eukaryotic cells.

How to use
Nocodazole was used at 40-100 ng/mL of culture medium for a duration of 12-18 hours in cell synchronization experiments.
For cell synchronization experiments, nocodazole is usually employed at a concentration of 40-100 ng/mL of culture medium for a duration of 12-18 hours. For inducing the formation of Golgi mi
NIST
acks incubate in 33 μM nocodazole for 3 hours.