商品编号


F6200



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Inhibitors



Size

5 mg

商品信息

SB216763 is a potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor. It competes with ATP and potently inhibits the activity α and β isozymes of GSK-3. It acts as neuroprotectant and prevents neuronal cell death induced by PI3-kinase pathway.

Additional Information






Product Name:

SB216763



Also Known As:

3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione



Catalog No.:

F6200



Size:

5 mg



CAS:

280744-09-4



Formula:

C
19
H
12
N
2
O
2
Cl
2



Molecular Weight:

371.22 Da



Form:

Lyophilized powder



Quality Assurance:

>98% by HPLC and NMR



Source:

Synthetic



Storage:

Elig
IBL
e for room temperature shipping. Store at -80°C upon receiving



PDF Data Sheet:

Download PDF datasheet



Image(s):

N/A



Shipping Method:

Room temperature shipping



References:

Cross DA,
et al
. (2001) J Neu
Roche
m 77:94-102.




Details

SB216763 is a potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor. It competes with ATP and potently inhibits the activity α and β isozymes of GSK-3. It acts as neuroprotectant and prevents neuronal cell death induced by PI3-kinase pathway.

Solubility:

> 10 mg/ml in DMSO