商品编号


F8121



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Inhibitors



Size

25 mg

商品信息

KU-60019 is a potent ATM kinase inhibitor (IC50 = 6.3 nM) in cell-free assays. Exhibits little to no nonspecific target effects against a panel of 229 protein kinases, including ATR and DNA-PKcs. It is a highly effective r
ADI
osensitizer.

Additional Information






Product Name:

KU-60019



Also Known As:

2-((2S,6R)-2,6-dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide



Catalog No.:

F8121



Size:

25 mg



CAS:

925701-49-1



Formula:

C
30
H
33
N
3
O
5
S



Molecular Weight:

547.67 Da



Form:

Lyophilized powder



Quality Assurance:

>98% by HPLC and NMR



Source:

Synthetic



Storage:

Elig
IBL
e for room temperature shipping. Store at -80°C upon receiving



PDF Data Sheet:

Download PDF datasheet



Image(s):

N/A



Shipping Method:

Room temperature shipping



References:

Golding SE,
et al
. (2009) Mol Cancer Ther, 8(10), 2894-2902.




Details

KU-60019 is a potent ATM kinase inhibitor (IC50 = 6.3 nM) in cell-free assays. Exhibits little to no nonspecific target effects against a panel of 229 protein kinases, including ATR and DNA-PKcs. It is a highly effective r
ADI
osensitizer.

Solubility:

10 mg/ml in DMSO