商品编号


EVS110A-1



品牌


SBI



公司


System Biosciences（SBI）



公司分类


exosome engineering


商品信息

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Overview:
Putting exosomes to work: Load your cargo directly into isolated exosomes

The EV Shuttle Kit harnesses a cell’s natural
ABI
lity to internalize exosomes for custom cargo delivery. Each kit includes exosomes isolated from either HEK293 cells or JAWS II mouse bone marrow dendritic cells and Exo-Fect—a novel transfection reagent that enables the transfer of RNAs, DNAs (including plasmids), and small molecules directly into isolated exosomes. Use the EV Shuttle Kit for a range of applications including cargo delivery for therapeutic development, virus-free creation of stable cell lines, and gene delivery in hard-to-transfect cells. And then pair your EV Shuttle Kit with our EV-Entry Reagent to maximize cargo delivery.



Easy-to-use with a fast and straightforward lo
ADI
ng protocol

Introduces a wide range of biomolecules directly into isolated exosomes:

RNAs, including siRNAs, miRNAs, and mRNAs

DNAs, including plasmids

Metabolites and other small molecules



Enables non-viral transduction and stable cell line creation

Provides an alternative gene delivery method for hard-to-transfect cells


How It Works:
Quickly and easily load cargo into isolated exosomes



Simply combine the isolated exosomes provided in the EV Shuttle Kit with Exo-Fect Reagent (also included in the Kit) and the nucleic acid or small molecule of your choice to generate exosome delivery vehicles. The Kit comes with all of the reagents you need to load cargo into exosomes and concentrate them for delivery to target cells. The protocol takes less than an hour and is highly efficient at lo
ADI
ng cargo into exosomes for transport and delivery.

The EV Shuttle Kit is also compat
IBL
e with the EV-Entry Reagent, which maximizes cargo uptake by recipient cells.